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Nature-Inspired Effects of Naturally Occurring Trace Element-Doped Hydroxyapatite Combined with Surface Interactions of Mineral-Apatite Single Crysta…

2022

Innovative engineering design for biologically active hydroxyapatites requires enhancing both mechanical and physical properties, along with biocompatibility, by doping with appropriate chemical elements. Herein, the purpose of this investigation was to evaluate and elucidate the model of naturally occurring hydroxyapatite and the effects of doped trace elements on the function of normal human fibroblasts, representing the main cells of connective tissues. The substrates applied (geological apatites with hexagonal prismatic crystal habit originated from Slyudyanka, Lake Baikal, Russia (GAp) and from Imilchil, The Atlas Mountains, Morocco (YAp)) were prepared from mineral natural apatite wit…

Chemical Phenomenahydroxyapatite; mineral apatite single crystals; FTIR; SEM-EDXS; X-ray diffraction; fibroblast cell culture; cell–surface interactionsQH301-705.5Cell SurvivalBiocompatible MaterialsCatalysisArticleInorganic Chemistryfibroblast cell cultureApatitesHumansBiology (General)Physical and Theoretical ChemistryQD1-999Molecular BiologySpectroscopyCell ProliferationMineralsSpectrum AnalysisOrganic Chemistryhydroxyapatitecell–surface interactionsGeneral MedicineFibroblastsComputer Science ApplicationsX-ray diffractionTrace ElementsChemistryDurapatiteFTIRSEM-EDXSmineral apatite single crystalsInternational Journal of Molecular Sciences

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PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
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LSLife Sciences
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